Extended Data Fig. 3: Cryo-EM data processing of hSLC19A1 bound to 2′3′-CDAS. | Nature

Extended Data Fig. 3: Cryo-EM data processing of hSLC19A1 bound to 2′3′-CDAS.

From: Recognition of cyclic dinucleotides and folates by human SLC19A1

Extended Data Fig. 3

a, Representative raw micrograph of hSLC19A1-Fab-2′3′-CDAS complex in nanodisc. b, Selected 2D class averages of hSLC19A1-Fab-2′3′-CDAS complex particles. c, Data processing flow chart. d, Gold-standard Fourier shell correlation curves of the final reconstruction. e, Local resolution distribution of hSLC19A1-Fab-2′3′-CDAS complex. f, Cryo-EM densities of transmembrane helices and intracellular loop IL6-7 at 5σ.

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