Extended Data Fig. 2: Pf life cycle without mosquitoes or humans.
From: In vitro production of infectious Plasmodium falciparum sporozoites
iPfSPZ were injected into mice containing humanized livers (FRGhuHep mice). Six and 7 days later the mice were transfused with human erythrocytes, and 6 h after the day 7 transfusion, blood was removed from the mice and cultured in vitro using standard methods. a, Parasites developed in these cultures to form Pf rings, trophozoites and schizonts; b. After induction, Pf gametocytes were produced in the cultures.
