Extended Data Fig. 7: Structural and sequence analysis of different merbecoviruses.
From: Close relatives of MERS-CoV in bats use ACE2 as their functional receptors
a, Superimposition of overall structures of NeoCoV RBD-Bat37ACE2 (red) and PDF-2180 RBD-Bat37ACE2 complexes (blue). b, Structures of RBDs from different merbecoviruses. MERS-CoV (PDB:4KQZ), HKU4 (PDB:4QZV), HKU5 (PDB:5XGR). c, RBD sequence alignments were generated with ClustalW and rendered with ESPript. Identical residues are highlighted with a red background and similar residues are coloured red in blue boxes.
