Extended Data Fig. 10: Syn-TEF treatment of RCC cell lines.

a, Quantitation of the percentage of propidium iodide-positive cells. P values are from a one-way ANOVA adjusted with Bonferroni correction for multiple comparisons. Results are mean ± s.e.m. (n = 3 biological replicates, except n = 2 biological replicates for Syn-TEF3 in 786-O). b, Live cell microscopy of Caki-1 and 786-O cells stained with propidium iodide (red) and Hoechst 33342 (blue). Scale bars, 100 μm. c, Relative cell density of RCC cell lines following treatment (72 h) with compounds (50 μM Syn-TEF or 0.1% DMSO vehicle, as indicated). Results are mean ± s.e.m. (ACHN and RCC-4 are n = 4 biological replicates, A498 and Caki-2 are n = 3 biological replicates).