Extended Data Fig. 2: The detailed analysis of TTC-pause structure. | Nature

Extended Data Fig. 2: The detailed analysis of TTC-pause structure.

From: Structural basis for intrinsic transcription termination

Extended Data Fig. 2

a. The previously determined consensus sequence for elemental pause sites18. b. The consensus sequence features from 100 previously identified E. coli intrinsic terminators11. c. The structural comparison of downstream dsDNA between TTC pause (pink and red) and TEC (gray). d. The structural comparison of RNA-DNA hybrid between TTC pause (pink and red) and TEC (gray). e. The path of single-stranded ntDNA of the transcription bubble in RNAP. f. The detailed interactions between single-stranded ntDNA of the transcription bubble and RNAP. Blue mesh, the cryo-EM map. Black dash, H-bond.

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