Extended Data Fig. 9: Control analysis of cell subsets from Xbp1WT and Xbp1Astro mice.
From: Identification of astrocyte regulators by nucleic acid cytometry
(a) FACS analysis of astrocytes and microglia in the CNS. n = 3 per group. (b) Validation of XBP1 KO by immunostaining. n = 6 images from n = 3 mice per group. Unpaired two-sided t-test. (c–d) FACS analysis of total CD4+ cells or FoxP3+, IFN𝛾+, and GM-CSF+ CD4+ T cell subsets from the (c) the spleen and (d) CNS of Xbp1WT and Xbp1Astro mice. (e) Pathways analyzed by pre-ranked gene set enrichment analysis (GSEA) of genes from RNA-seq data comparing Xbp1WT and Xbp1Astro mice.
