Extended Data Fig. 5: Sequence conservation of the Dap/Dap1b/Dapl1 protein family and RNA expression of ribosome-associated factors. | Nature

Extended Data Fig. 5: Sequence conservation of the Dap/Dap1b/Dapl1 protein family and RNA expression of ribosome-associated factors.

From: A molecular network of conserved factors keeps ribosomes dormant in the egg

Extended Data Fig. 5

a, Protein sequence alignment of the Dap/Dap1b/Dapl1 protein family illustrates conserved motifs. Vertebrates have two paralogs, namely Dap1b/Dapl1 and Dap. Invertebrates only encode one homolog (Dap1) that clusters in between Dap1b/Dapl1 and Dap proteins. b, Zebrafish mRNA expression levels (PolyA+ RNA-seq31,82) of eif5a/eif5a2 (purple), eef2b (orange), dap1b/dap (green) and habp4 (blue) during oogenesis and embryogenesis. c, Xenopus mRNA expression levels of all paralogs of eif5a, eef2, dap, dapl1 and habp4 derived from riboMinus-seq data84. d, mRNA expression levels of zebrafish eif5a/eif5a2, eef2b, dap1b/dap and habp4 in adult tissues85. TPM, transcripts per million.

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