Extended Data Fig. 7: Motif F residue interactions with the incoming NTPs. | Nature

Extended Data Fig. 7: Motif F residue interactions with the incoming NTPs.

From: Structural basis for substrate selection by the SARS-CoV-2 replicase

Extended Data Fig. 7

(a–e) Analysis of the active sites of structures (S1–S5) illustrate that K545 and R555 interact differentially with each of the incoming nucleotides. H-bonds are depicted as dotted-cyan lines. (f,g) 2D schematics illustrating the set of interactions between RDV-TP (f) and ATP (g) and the active site.

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