Extended Data Fig. 4: Single-cell frequencies correlate with clinical subgroups in patients with brain tumours.
From: Single-cell spatial immune landscapes of primary and metastatic brain tumours
a, Cell density comparisons between clinical subgroups of patients, corresponding to Supplementary Fig. 8. Within each row, bubble colour indicates the clinical subgroup (A term versus B term, right) with higher cell type representation; bubble size indicates P-value. Two-sided student’s t test, unpaired unless indicated otherwise; paired analyses are from patient-matched samples. b, Cell frequencies as a percentage of total cells per image in glioblastoma tumours with low T cells (<5% of TME, n = 144 images) versus high T cells (>5% of TME, n = 13 images). Data are mean ± s.e.m.; two-sided student’s t test. c, Mean overall survival time of glioblastoma patients (for whom this information was available) with low T cells (<5% of TME, n = 142 images) versus high T cells (>5% of TME, n = 13 images). Data are mean ± s.e.m.; two-sided student’s t test.
