Extended Data Table 3 Clinical Associations with timing and modes of metastatic divergence

From: The evolution of non-small cell lung cancer metastases in TRACERx

  1. Age, smoking status, histology, disease stage, pleural and lymphovascular invasion, resection margin, presence of pre-operative circulating tumour DNA (ctDNA) and location of disease recurrence were explored. Early divergence was associated with being a smoker, and polyclonal dissemination was associated with extrathoracic disease recurrence. All significant (p < 0.05) results are shown in red with corresponding statistical tests used. All tests performed were two-sided.
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