Extended Data Fig. 6: Liver and hematological parameters of Tet2−/− bone marrow transplanted mice.
From: Clonal haematopoiesis and risk of chronic liver disease
a, Ldlr−/− mice were transplanted with Tet2−/− (n = 25) or control vavCre+ (wt; n = 20) bone marrow cells and fed Western diet for 10 weeks. b, B6.SJL mice were transplanted with Tet2−/− (n = 19) or control vavCre+ (wt; n = 12) bone marrow cells and fed CDAHFD for 11 weeks. c, C57BL/6J mice were transplanted with Tet2−/− (n = 12) or control vavCre+ (wt; n = 13) bone marrow cells and fed CDAHFD for 19 weeks. After the prescribed dietary periods, mice were sacrificed and terminal liver weight and peripheral blood chimerism and hematological parameters were measured. Data from one (c) or two independent experiments (a, b) are shown. WBC, white blood cell count; Hgb, hemoglobin; Hct, hematocrit; RBC, red blood cell count; Plt, platelet count.
