Fig. 2: Cryo-EM structure of Rpd3S complex bound to H3K36me3 nucleosome.
From: Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S
a, A model of the core Rpd3S complex bound to the H3K36me3 modified nucleosome in the close state. b, A stereo view of contact between the core Rpd3S complex and the H3K36me3 modified nucleosome in the close state. Sin3, Rpd3, Eaf3 and Rco1 are shown in cartoon form. The nucleosome is shown in surface representation. The invisible left arm region is coloured grey. c, Two views of the superimposition of close and loose state of core Rpd3S complex are shown in orange yellow and pale cyan, respectively. H3 and H4 of the histone octamer are highlighted in cartoon form. d, A model of the CHD domains with the H3K36me3 modified nucleosome. The tails of histone H2A and H2B are labelled with arrows. The positions of nucleosomal DNA are labelled as SHL positions.
