Extended Data Table 2 NTS and SBI-553 induced GRK2, β-arrestin-2 and Gq recruitment to NTSR1

From: GPCR activation and GRK2 assembly by a biased intracellular agonist

  1. Data represent mean pEC50 (pEC50 ± S.D.), Emax (Emax ± S.D.), Emin (Emin ± S.D.). Data were generated and graphed as means ± S.D. of at least three independent experiments (n = 3) performed in duplicate. The Emin and Emax were normalized by NTS-induced WT receptor within each individual experiment, with the basal activity as zero, while the fitted Emax as 100. UD, undetectable.
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