Extended Data Fig. 7: Analysis of PIEZO1 Blade Cooperativity.
From: Direct observation of the conformational states of PIEZO1
Histograms of inter-blade distances for each edge of the triangle formed by fluorophore positions of isolated triple labeled PIEZO1 molecules and the ratios of each of these edges. a, Inter-blade distances and edge ratios for TCO*K 103 in the absence of stimulus (from Fig. 2e). b, Inter-blade distances and edge ratios for TCO*K 103 with a 120 mOsm hypotonic shock stimulus (from Fig. 4b). c, Inter-blade distances and edge ratios for TCO*K 670 in the absence of stimulus (from Fig. 3c).
