Extended Data Fig. 3: State-specific regulons reveal a stepwise differentiation linked to the wound healing phases.

a. Analysis pipeline to determine the collection of transcription factors (programme) and their associated regulons for each fibroblastic state. b-e. UMAPs of programme (left) and regulon scores (centre), and their overrepresented GO terms (right) for the fascia (b), proinflammatory (c), proto-myofibroblast (d), and myofibroblast states (e). f. Scheme of the fibroblastic states along the trajectory and their phenotype revealed from scRNAseq analysis.