Extended Data Fig. 9: Mappability normalization of peak accessibility.
From: Conserved and divergent gene regulatory programs of the mammalian neocortex
a. 100 base-pair mappability rate47 for each peak across conservation levels (above), and the 4 kb centred around each peak (below). Box plots encompass 25th to 75th percentiles; central lines represent medians; whiskers represent 1.5 times the interquartile interval. b. A scatter plot highlighting the effect of mappability on reads in each peak (N = 384,412), and the 4 kb region centred around each peak. c. Box plots highlighting the change in number of reads as a function of region mappability for each peak, and 4 kb region centred around each peak. Box plots encompass 25th to 75th percentiles; central lines represent medians; whiskers represent 1.5 times the interquartile interval. d. A scatter plot highlighting the correspondence between mappability normalized accessibility for each cell type peak and 4 kb region centred around each peak. e. Box plots highlighting the change in number of mappability normalized reads as a function of region mappability for each peak(N = 384,412), and 4 kb region centred around each peak. Box plots encompass 25th to 75th percentiles; central lines represent medians; whiskers represent 1.5 times the interquartile interval.
