Extended Data Fig. 8: Slide-tags snRNA-seq on human melanoma.
From: Slide-tags enables single-nucleus barcoding for multimodal spatial genomics
a, Schematic representation of Slide-tags snRNA-seq and Slide-tags multiome (Fig. 4) profiled regions across tumour 1 and 2 compartments. b, UMAP embeddings of snRNA-seq profiles coloured by cell type. c, Spatial mapping of cell types. d, Spatial mapping of profiled cell types. e, Expression of select cell type marker genes and melanoma cell state marker genes. f, Inferred copy number alterations from transcriptomic data. NT indicates a representative subset of non-tumour cells. All scale bars denote 500 μm. T reg = T regulatory cells, mDC = myeloid dendritic cells, Mono-mac = monocyte-derived macrophages, pDC = plasmacytoid dendritic cells.
