Fig. 4: The oscillatory sequences transcend periods of running and immobility.
From: Minute-scale oscillatory sequences in medial entorhinal cortex
a, Top, raster plot of one recorded session (520 neurons). Time bins in aquamarine indicate that the mouse ran faster than 2 cm s−1. Second from top, expanded view showing 160 s of neural activity. Third from top, instantaneous speed of the mouse. Bottom, position of the mouse on the wheel. b, Probability of observing the oscillatory sequences given that the mouse was either running or immobile (median probability during running and immobility was 0.93 and 0.69, respectively; two-sided two sample Wilcoxon signed-rank test, n = 10 sessions over 3 mice, P = 0.002, W = 55). c, Fraction of immobility epochs with oscillatory sequences as a function of length of the immobility epoch (data are mean ± s.d.). For each length bin, the fraction of epochs was averaged across sessions. Orange, recorded data (n = 10 per length bin); blue: shuffled data (n = 5,000 per length bin, 500 shuffled realizations per session). Recorded versus shuffled data: P ≤ 2.62 × 10−6, 4.7 ≤ Z ≤ 47.5, two-sided Wilcoxon rank-sum test. d, Number of completed laps as a function of sequence number for one mouse. Each dot indicates one sequence. Dashed lines indicate separation between recorded sessions.
