Fig. 4: Application and mechanistic investigation of the 1,3-difunctionalization of alkenes.
From: Stereodivergent 1,3-difunctionalization of alkenes by charge relocation
a, Synthesis of 4-ipomeanol and other biologically active molecules43. b, Proposed mechanism of 1,3-alkene difunctionalization, involving charge relocation. c, Mechanistic investigations support the hypothesis that nascency of the charge does not affect the constitution of the obtained product (Supplementary Information). d, Complete stereocontrol for the formation of a 1,2,3-trisubstituted cyclohexane.
