Extended Data Fig. 8: HPRT1, HPRT1R in mESCs replicate correlates. | Nature

Extended Data Fig. 8: HPRT1, HPRT1R in mESCs replicate correlates.

From: Synthetic reversed sequences reveal default genomic states

Extended Data Fig. 8

Scatterplots showing correlation between sequencing assays for HPRT1 on chrX (a), HPRT1R on chrX (b), HPRT1R on chr3 (c), HPRT1RnoCpG on chrX (d), and HPRT1RnoCpG on chr3 (e). Plots compare signal, as bigWig scores, over 10 kb windows for the combined synthetic locus and mouse genome, for ATAC-seq, H3K4me3, RNAP2, H3K27ac, and H3K27me3 CUT&RUN, and RNA-seq. Both replicates (Rep. 1, Rep. 2) for each of the independent clonal isolates (Clone 1, Clone 2) are compared, and Pearson’s correlation (p) between each replicate is reported.

Back to article page