Table 1 Sequence featured of the synthetic locus
From: Synthetic reversed sequences reveal default genomic states
Synthetic locus | ||||
|---|---|---|---|---|
Feature | HPRT1 | HPRT1R | HPRT1RnoCpG | |
Length | 100,667 | 100,667 | 95,067 | |
GC content | 0.41 | 0.41 | 0.38 | |
Dinucleotides | AA | 6,601 | 6,601 | 6,601 |
AC | 4,942 | 6,952 | 5,803 | |
AG | 7,012 | 5,734 | 6,883 | |
AT | 7,491 | 6,759 | 6,759 | |
CA | 6,952 | 4,942 | 5,743 | |
CC | 4,261 | 4,261 | 3,442 | |
CG | 1,202 | 4,499 | 0 | |
CT | 7,038 | 5,751 | 6,583 | |
GA | 5,734 | 7,012 | 6,211 | |
GC | 4,499 | 1,202 | 726 | |
GG | 4,348 | 4,348 | 4,455 | |
GT | 5,368 | 7,388 | 6,556 | |
TA | 6,759 | 7,491 | 7,491 | |
TC | 5,751 | 7,038 | 5,797 | |
TG | 7,388 | 5,368 | 6,609 | |
TT | 7,415 | 7,415 | 7,415 | |
CpG | Expected | 4,291 | 4,291 | 3,386 |
Ratio | 0.28 | 1.05 | 0 | |
Yeast TFBSsa | 5,159 | 18,191 | 13,284 | |
Mouse TFBSsb | p-val < 0.001 | 24,578 | 19,782 | 21,897 |
q-val < 0.01 | 1,132 | 707 | 882 | |
