Extended Data Fig. 6: No change in apoptosis and neuronal markers in control and Crym KO astrocytes.
From: Crym-positive striatal astrocytes gate perseverative behaviour
a–c, Representative images of TUNEL (green), mCherry (red), and DAPI (blue) in control (a), Crym KO (b), and control + DNase1 (c) mice. d, Scatter graphs show the number of DAPI positive cells (left) and TUNEL positive cells (right) (n = 7 mice for control and Crym KO and n = 6 mice for control + DNase 1, two-tailed two-sample t-test). There were no differences in the number of DAPI+ cells between controls and Crym KO mice and no TUNEL staining was observed, except for the positive control. e,f, Representative images (e) and scatter graphs (f) of the number of NeuN positive cells in 7 control mice and 8 Crym KO mice (two-tailed two-sample t-test). g,h, Representative images (g) and scatter graphs (h) of the number of DARPP-32 positive cells in 9 control mice and 8 Crym KO mice (two-tailed two-sample t-test). Average data are shown as mean ± s.e.m. and all statistics are reported in Supplementary Table 5.
