Extended Data Fig. 2: CAR T cell transduction efficiency and transgene overexpression.
From: FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy
a, Schematic of anti-Her2 CAR with Myc binding domain and detection of Myc tag in CAR T cells transduced with the indicated transcription factors. Representative histograms of 3 independent transductions. b, Expression of indicated transcription factors in murine CD8+NGFR+ CAR T cells (b) or human FACS sorted CAR T cells as determined by qRT-PCR. Data represent the mean ± SD of technical triplicates from two independent experiments. Statistics determined by unpaired two-sided t test, (*p < 0.05, ***p < 0.001, ****p < 0.0001). Source data are provided in the Source Data file.
