Extended Data Fig. 4: Temporal evolution of reactivation across recorded sessions.
From: Sleep loss diminishes hippocampal reactivation and replay
Reactivation assessed using the explained variance (EV) metric (NSD (black), SD (red) and RS (blue)), in thirteen sessions from six different animals (3 male and 3 female, with 3 sessions from 2 animals (1 male, 1 female) excluded due to an insufficient number of stable neurons), as in Fig. 3a. Chance level (REV) is shown in maize. Solid lines show the mean and shaded regions show the standard deviation of EV/REV across all 15 min windows in POST. Each row provides session(s) from one animal, with number of putative pyramidal neurons and cell pairs used to calculate EV specified inside each panel. Hypnograms above panels depict sleep/wake history in active wake (AW), quiet wake (QW), rapid eye movement (REM) sleep and non-REM (NREM) sleep, with sleep deprivation/recovery sleep in red/blue and natural sleep in black. Animals’ tracked positions on the novel maze (purple) are depicted on the right of the panels along with the session recording day.
