Extended Data Fig. 4: Schematic of interactions between IS621 and nucleic acids. | Nature

Extended Data Fig. 4: Schematic of interactions between IS621 and nucleic acids.

From: Structural mechanism of bridge RNA-guided recombination

Extended Data Fig. 4

A43/A67/A116/A150 and G48/G72/G121/G155, common structural features in the TBL and DBL, and the core nucleotides (tC8/tT9/tA6*/tG7* and dC8/dT9/dA6*/dG7*) are highlighted in bold. G48/G72/G121/G155 and U159, which adopt the syn conformation, are shown in italics. The Mg2+ ions are depicted as cyan circles. Non-canonical base-pairs are indicated by red squares. The IS621 residues that interact with the nucleic acids through their main chains are shown in parentheses.

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