Extended Data Fig. 8: Interactions of M. smegmatis ATP synthase and BDQ.
From: Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587
a, Structural comparison between M. tuberculosis ATP synthase subunits a/c and that of M. smegmatis. b, The three binding sites for TBAJ-587 to M. smegmatis ATP synthase. c, Interactions between BDQ and M. smegmatis ATP synthase in three binding sites. BDQ and the surrounding residues within 5.0 Å are shown in sticks. d, Two-dimensional plot of the BDQ with M. smegmatis ATP synthase interactions. Hydrogen bonds are represented by the black dashed lines.
