Fig. 4: Exploring use cases of PathChat.
From: A multimodal generative AI copilot for human pathology

a–e, Beyond evaluating PathChat on answering multiple-choice and single-turn open-ended questions, we explored other use cases. The panels contain examples that involve a follow-up from users in the form of interactive, multi-turn conversations. These examples are illustrative in nature and intended to complement our quantitative evaluation of PathQABench. a, PathChat summarized key morphological features in an histology image. Based on the clinical context, it could reasonably infer the primary origin of the tumour. b, PathChat is familiar with different cell markers and can potentially help by guiding IHC interpretations. c, PathChat understands and can attempt to follow well-known guidelines on tumour grading, in this case, the Gleason grading system for prostate adenocarcinoma. d, PathChat can describe tumour tissue and cell morphology, infer a diagnosis and correctly suggest potential IHC findings grounded in relevant background knowledge about the suspected malignancy. e, PathChat can potentially be consulted to perform human-in-the-loop differential diagnosis that may require several rounds of an IHC workup. Scale bars, 200 µm.