Fig. 4: Recovery profile dynamics in PBMCs.
From: The Space Omics and Medical Atlas (SOMA) and international astronaut biobank
a, Number of DEGs from PBMC snRNA-seq for each cell type during the flight, recovery and longitudinal profiles (adjusted two-sided P < 0.05, |log2FC| > 0.5). NK, natural killer. b, Fraction of DEGs shared with FP1 at RP1, RP2 and LP2 for each cell type. c, Directionality of log2FC between FP1 and RP1 and RP2 for DEGs present in both profiles. d, Bar chart of pathways of DEGs present in RP1 that were absent in FP1 in monocytes and T cells. Bars are shaded by the false discovery rate (FDR) value, and the enrichment ratio is on the x axis.
