Fig. 3: Analysis of E. faecalis phage-derived endolysin in E. faecalis-mono-colonized gnotobiotic GVHD mice.
From: An enterococcal phage-derived enzyme suppresses graft-versus-host disease
a, Colony-forming units (CFU) (left) and percentage CFU (right) of E. faecalis in faecal samples before and after transplantation. Each dot and line represent the data from one faecal sample. Significance was determined using the Wilcoxon rank-sum test (two-sided). Patient031_14_8: n = 8 for endolysin-treated mice, n = 6 for vehicle-treated mice. Patient009_35_10: n = 8 for endolysin-treated mice, n = 8 for vehicle-treated mice. Patient015_56_7: n = 8 for endolysin-treated mice, n = 7 for vehicle-treated mice. b, Kaplan–Meier survival plots of endolysin-treated mice and vehicle-treated mice. Significance was determined using the log-rank test (two-sided). The numbers of endolysin-treated mice and vehicle-treated mice for each of the patient samples are as in a.
