Fig. 6: Bovine H5N1 virus binds to both α2,3 and α2,6 sialic acid residues.
From: Pathogenicity and transmissibility of bovine H5N1 influenza virus
Fourfold serial dilutions of α2,3 and α2,6 sialylglycopolymers adhered to microtitre plates were incubated with 32 haemagglutination (HA) units of the indicated viruses or PBS (negative control). After washing, virus binding was detected by an anti-HA human monoclonal antibody (CR9114) and an HRP-conjugated secondary antibody. The absorbance values for each condition with each virus or PBS are shown. Each dot represents a single biologically independent replicate value.
