Extended Data Fig. 6: Summary of spatial activity map changes of telencephalic place cells under different environmental manipulations.
From: A population code for spatial representation in the zebrafish telencephalon
a, The median of PF correlation (top), PV correlation (middle), and PF shift (bottom) for individual fish. Gray dots are comparisons between the early (1st half) and late (2nd half) stages of the 1st session. The red dots are comparisons made between the 1st session and the 2nd session. Experiments from Figs. 4–6 are represented on the horizontal axis: chamber rotation (Fig. 4m), landmark removal (Fig. 4e), wall morphing (Fig. 4i), wall rotation (Fig. 5m), fish removal with no change in the chamber (Fig. 5a), landmark removal with fish removal (Fig. 5e), wall morphing with fish removal (Fig. 5i), and wall morphing with landmark removal and fish removal (Fig. 6a). Data from the same fish are connected by gray lines. The results of statistical tests are marked for each fish separately (one-sided Wilcoxon signed-rank test, *** for p < 10−5, ** for p < 0.001, * for p < 0.01, n.s. for p ≥ 0.01, see Supplementary Table 1 for exact p-values). b, The relationship between PF overlap and PF correlation for different experiments. Each dot represents a PC. PF overlap is defined as the intersection over union of its PFs in the two sessions or between the early and late half of session 1 (as control). Orange dots denote cells with significant PF correlation (one-sided shuffle test, p < 0.05). Briefly, to test the significance of the PF correlation, we circularly permuted (~ 1000 times, corresponding to the number of bins in the map) the observed spatial activity map of session 2 (or the 2nd half of session 1 in controls), and recalculated the PF correlation across sessions for each permutation to construct the null distribution for a one-sided shuffle test. c, The dropout rates of PCs for individual fish (gray, within session control; red, cross-session comparison, as defined in a). A dropout cell is defined as a cell that does not retain significant PF correlation between sessions and is only classified as a PC in the first but not second session.
