Extended Data Fig. 5: Suppression of the human type I interferon network in Fga–/– mice after SARS-CoV-2 infection.
From: Fibrin drives thromboinflammation and neuropathology in COVID-19
Overlay of the differentially expressed genes in the lung from Beta-infected Fga–/–mice on the “Type I interferon induction and signalling during SARS-CoV-2 infection - Homo sapiens” pathway. Gene nodes are coloured with red-blue gradient to indicate degree of log2 fold change in gene expression between WT and Fga–/– mice. Red borders indicate statistical significance of unadjusted P < 0.05 calculated by two-sided quasi-likelihood F-test implemented in edgeR. https://new.wikipathways.org/pathways/WP4868.html.
