Extended Data Fig. 11: Disease-associated genes in microglia in Delta-infected mice.
From: Fibrin drives thromboinflammation and neuropathology in COVID-19
a, Representative RNAscope images of Trem2, Cst7, and Spp1 (red) mRNA expression in Iba-1 immunoreactive microglia (green) within the hippocampus of Delta-infected K18-hACE2 mice. b, Quantification of Trem2, Cst7, and Spp1 mRNA expression as percentage of total Iba-1+ cells in the hippocampus. Data are from n = 5 mice per group. Two-tailed Mann-Whitney test. Scale bars, 20 μm. All data are mean ± s.e.m. UI, uninfected.
