Extended Data Fig. 2: Computational modelling of fibrinogen-Spike protein interactions.
From: Fibrin drives thromboinflammation and neuropathology in COVID-19
a, Predicted computational complex model using crystal structure of fibrinogen (PDB ID: 3GHG) and cryoEM structure of Spike (PDB ID: 6VSB). b, Surface of this complex. c, Schematic representation of intermolecular interface of this predicted model. d, 3D representation of interface shown by side chain of the few residues involved in interaction. e, Intermolecular interface showing atom-wise interaction with all the residues involved in the interaction including a hydrogen bond highlighted in green dashed line using LigPlot +, v.2.2. https://www.ebi.ac.uk/thornton-srv/software/LigPlus/.
