Extended Data Fig. 3: Detailed genetic mutation prediction results organized by cancer types.
From: A pathology foundation model for cancer diagnosis and prognosis prediction
Prediction performance of prevalent genetic mutations (n = 11,483) and targeted-therapy-associated genetic mutations (n = 6,013) is shown. The detailed sample counts for each genetic mutation are available in Supplementary Tables 17, 18. CHIEF predicted several prevalent mutations (e.g., TP53 in ACC, LGG, and UCEC) with AUROCs > 0.80. The mean ± 95% confidence interval is shown for each prediction task. Error bars represent the 95% confidence intervals estimated by 5-fold cross-validation (5 independent runs).
