Extended Data Fig. 10: Structurally aligned E1 glycoprotein phylogenies.

Protein sequences were aligned using their 3Di structural representation (see Methods for details). Phylogenies were reconstructed using 3Di sequence alone (top), amino acid (AA) sequence alone (middle) or combined 3Di and AA sequence. Right hand trees are derived from alignments trimmed with a gap threshold of 35%. Scale bars indicate substitutions per site for either the 3Di, AA or combined sequences, respectively. Tip shapes are colour-coded by genus/subclade as in Fig. 1a. All phylogenetic trees are provided in the associated Zenodo repository.