Extended Data Fig. 5: Hydrodynamic DNA delivery of ANP and BNP expression vectors in normotensive mice induced a sustained reduction in systolic blood pressure.
From: Agonist antibody to guanylate cyclase receptor NPR1 regulates vascular tone

ANP and BNP overexpression resulted in systolic blood pressure reduction of over 30 mmHg. Key: black circles, control; red squares, ANP; purple triangles, BNP. ANP, atrial natriuretic peptide; BNP, brain natriuretic peptide; HDD, hydrodynamic delivery.