Extended Data Fig. 9: REGN5381-induced plasma cGMP production in healthy volunteers. | Nature

Extended Data Fig. 9: REGN5381-induced plasma cGMP production in healthy volunteers.

From: Agonist antibody to guanylate cyclase receptor NPR1 regulates vascular tone

Extended Data Fig. 9

Mean ± standard error change from baseline in plasma cGMP levels following administration of study treatment (pooled placebo, grey bar; REGN5381 10 mg, light blue bar; REGN5381 30 mg, blue bar; REGN5381 100 mg, dark blue bar). cGMP, cyclic guanosine monophosphate; IV, intravenous; SE, standard error.

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