Extended Data Fig. 2: Multiple Sequence alignment of SPIN1 and the SPOCD1 ß-hairpin region.
From: Two-factor authentication underpins the precision of the piRNA pathway

a, Multiple sequences alignment of SPIN1 from representative vertebrates. The domain structure of mouse SPIN1 (Q61142) is indicated underneath the alignment in grey. b, Multiple sequence alignment of the SPOCD1 ß-hairpin region with representative vertebrate SPOCD1 sequences. Secondary structure elements from the AlphaFold2 model of mouse SPOCD1 (B1ASB6) are shown below with grey arrows representing a ß-strand. a-b, sequences are coloured according to sequence identity. Numbering above according to mouse sequence.