Extended Data Fig. 11: Effect of thiamine on BTh invertases and thiamine biosynthesis and uptake loci.
From: Intragenic DNA inversions expand bacterial coding capacity
(A) Log2RPKM values for all annotated invertases in BTh are shown across the thiC mutant backgrounds and thiamine concentrations. Axis is clustered with pheatmap’s default parameters (Euclidean). (B) Log2RPKM values for transcript levels of all genes in the thiamine biosynthesis pathway (BT0647-0653) and genes involved in uptake of thiamine (BT2390, BT2396) are denoted. (C) Intensity of ThiH protein as determined by mass spectrometry using data-independent acquisition. UR, unlocked thiC reverse; LR, locked thiC reverse.
