Fig. 4: Example eigencircuits.
a, Neurons with top five loadings on eigenvector 1. b, First eigenvector of the fly effectome. c, Linear and rectified dynamics upon stimulation by first eigenvector (a.u., arbitrary units). d, Synaptic count and sign between neurons. e, Circuit diagram representation of synaptic weight and sign. f, Visual stimulation simulation. VCH and DCH are given sustained stimulation for 150 ms, simulating BTF motion on the right side of the fly (fly on the left; solid brown and yellow, high sustained response). All neurons were given sustained stimulation for 150 ms, simulating BTF motion on both sides of the fly, which leads to inhibited responses of VCH and DCH (fly on the right; dashed brown and yellow below solid). g, Neurons with top four loadings on eigenvector 45. h, All loadings for eigenvector 45. i, Linear and rectified dynamics (left) upon stimulation by eigenvector 45 (right). j, Synaptic count and sign between nine neurons with top loadings on eigenvector 45. k, Simulation of visual stimulation. Left, simulation of a 0° visual stimulus, with strong input to the 0°-preferring neuron (light blue trace) and sustained background input to all other neurons. The network response exhibits WTA dynamics, in which all neurons respond transiently to stimulus onset, but only the neuron with maximal response remains active for the entire stimulus duration. Right, similar results for a 90° stimulus and 90°-preferring neuron (green trace).
