Extended Data Fig. 14: Additional optical CaMKII inhibition experiments during BTSP.
From: Dendritic, delayed, stochastic CaMKII activation in behavioural time scale plasticity
a, Schematic of an additional CaMKII inhibition experiment shown in (b). CaMKII was inhibited for 2 mins,15 s after the BTSP protocol (green). b, Left: Representative EPSP traces of a stimulated spine (average of 10 traces) before and after BTSP induction in paAIP2 labeled neurons. Right: Normalized EPSP time course in response to BTSP in stimulated and adjacent spines; Arrow depicts BTSP induction. c, Normalized EPSC time course in adjacent spines of BTSPvc, BTSPvc+depol and Uncage+depol experiments, showing no potentiation after BTSP induction. The number of cells is mentioned in the figure panel.
