Extended Data Fig. 5: Characterization of methylation information retrieval. | Nature

Extended Data Fig. 5: Characterization of methylation information retrieval.

From: Parallel molecular data storage by printing epigenetic bits on DNA

Extended Data Fig. 5

a, Retrieved images under different thresholds of methylation calling. The recovery of 8 images (rows) were visualized under 11 different methylation calling thresholds from 0 to 100% (columns). The relationship between threshold and accuracy is shown in the top panel. b, The fitting results of 32 methylation sites on the DNA templates. For each methylation site, the results of methylation calling are collected (bar plots) and then used for fitting. The best fitting results (with minimal fitting loss) are illustrated as red lines. In each subplot, the x-axis shows the methylation probability, and the y-axis is the maximum-minimum normalized counts.

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