Fig. 5: Glucose-induced activation of NNC2215 during a GTT in streptozotocin-diabetic rats.
From: Glucose-sensitive insulin with attenuation of hypoglycaemia
a,b, The glucose infusion rate (GIR) (a) and plasma glucose (b) profiles before (0–150 min), during (150–210 min) and after (210–300 min) a GTT in streptozotocin-diabetic rats receiving i.v. infusion of NNC2215 (84 pmol kg−1 min−1), human insulin (20 pmol kg−1 min−1) or human insulin (20 pmol kg−1 min−1) plus additional 10 pmol kg−1 min−1 (+50%) during the GTT. Data are mean ± s.e.m. n = 5 (NNC2215 and human insulin) and n = 7 (human insulin +50%) rats.
