Extended Data Fig. 9: The expansion of Ir41 and Ir7 clades in Ae. albopictus, and a putative sugar- or amino acid-sensing Gr encoded in Ae. albopictus but not in Ae. aegypti.
From: Mosquito taste responses to human and floral cues guide biting and feeding
a-b, Cluster analysis of the protein sequences of Irs annotated in the Ae. albopictus genome (AalbF3, [Boyle et al.36, Insects]) and Drosophila melanogaster, for the Ir41 clade (a), and Ir7 clade (b). Dots indicate transcripts that are detected in the labellum ( ≥ 1 TPM). Drosophila transcript expression data from [Wang et al.37, eLife]. Three genes (Ir41g-1, ir41m, and Ir41p) were not included in this analysis due to incomplete open reading frame in the current genome. c, Cluster analysis of the protein sequences of all Grs annotated in the Ae. albopictus genome (AalbF3, [Boyle et al.36, Insects]). The Ae. albopictus Gr82 (boxed) shares most similarity with Gr13. Gr44 was not included in this analysis due to its incomplete open reading frame in the current genome. Dots indicate transcripts that are detected in the labellum ( ≥ 1 TPM). d, Gene annotation of orthologous region that includes AAEL000033, a gene predicted to encode the integrator complex subunit 10 that is near a gustatory receptor gene; and Grs from Ae. albopictus (top) and Ae. aegypti (bottom). Ae. albopictus locus encodes an additional gustatory receptor, Gr82, relative to Ae. aegypti.
