Extended Data Table 1 Association between MLC score sum (MSS) and blood cell counts in the UK Biobank

From: Quantifying constraint in the human mitochondrial genome

  1. Table showing β coefficients, standard error (SE), and p-values from linear regression models of the association between platelet or neutrophil count and heteroplasmy count and or mtDNA local constraint (MLC) score sum (MSS). Regressions were run as separate models (‘Single’) or together in the same model (‘Combined’, where both heteroplasmy count and MSS were included in the same model), and adjusted for age, sex and smoking status. Significant p-values, computed using a two-sided test, are bolded.