Extended Data Fig. 6: Inflammation and haematopoiesis in MI and MI + SF mice.
From: Myocardial infarction augments sleep to limit cardiac inflammation and damage
a, Flow cytometry enumeration of cardiac cells in MI and MI + SF mice. n = 7 MI; n = 8 MI + SF. b, Enumeration of monocytes and neutrophils in the infarcts of mice 3 days after receiving a ‘large’ MI and sleeping habitually or exposed to SF. n = 5 mice per group. c, Flow cytometry enumeration of blood leukocytes in MI and MI + SF mice. n = 11 MI on day 3; n = 12 MI + SF on day 3; n = 7 MI on day 7; n = 8 MI + SF on day 7; n = 7 MI day 21 monocytes; n = 9 MI + SF day 21 monocytes; n = 11 MI day 21 neutrophils; n = 12 MI + SF day 21 neutrophils. d, Flow cytometry gating and enumeration of progenitor cells in the BM of MI and MI + SF mice. Each data point represents an individual mouse. e, Analysis of BrdU incorporation into BM progenitor cells of MI and MI + SF mice 3 days after infarct. n = 5 per group. Data are mean ± s.e.m. Statistical analysis was done using two-tailed unpaired t-tests. Experiments were conducted in female mice. *p < 0.05, **p < 0.01, ***p < 0.001.
