Extended Data Fig. 1: SnRNA-seq analysis of mouse ARC neurons.
From: Leptin-activated hypothalamic BNC2 neurons acutely suppress food intake
a, Single-cell UMAP plot of the male ARC (N = 6 adult WT mice). b, Violin plot showing known markers of different cell types: neurons (Tubb3, Snap25, Syt1, Elavl4), tanycytes (Rax), ependymocytes (Ccdc153), oligodendrocyte cells (Mag, Olig1, Cspg4, Cd9, Pllp), macrophages (Aif1, C1qa), endothelial cells (Slco1c1, Cldn5), mural cells (Mustn1), astrocyte (Gfap, Sox9), vascular and leptomeningeal cells (Lum), pituitary cells (Tshb), pars tuberalis cells (Cck), ependymal cells (Vim). Clusters 20/21/23/24 are non-neuronal clusters. c, Dot plot displaying the expression of cluster-specific marker genes (identified in this study) across neuronal clusters with the ARC from Campbell et al.22.
