Extended Data Table 2 Pathogenic missense mutations in apoB100-LDLR binding interfaces

From: Structure of apolipoprotein B100 bound to the low-density lipoprotein receptor

  1. aFor the APOB mutations, the LDLR LA module whose binding to apoB100 is affected by the APOB mutation is indicated in brackets. For the LDLR mutations, the LA module containing the mutation is in parentheses. bLink to ClinVar (https://www.ncbi.nlm.nih.gov/clinvar/) database which provides clinical and functional validation for each variant. N.D., not determined; βp, β-propeller of LDLR.
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