Extended Data Fig. 4 | Nature

Extended Data Fig. 4

From: MCM double hexamer loading visualized with human proteins

Extended Data Fig. 4

a, Nuclease footprinting assay with yeast proteins using ATP or ATPγS. b, Representative micrograph of the human MCM recruitment reaction using ATPγS. c, 2D averages of nucleosomes, MCM, hOCCM and hMO* were observed in the dataset. The box size 449 Å. d, Angular distribution of the hOCCM structure. e, Fourier shell correlation plot for the hOCCM structure. f, Three rotated views and one cut-through view of the hOCCM structure, color-coded according to the local resolution as estimated in cryoSPARC. g, Angular distribution of the hOC1M structure. h, Fourier shell correlation plot for the hOC1M structure. i, Three rotated views and one cut-through view of the hOC1M structure, color-coded according to the local resolution as estimated in cryoSPARC.

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